Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA
Piriformis Syndrome – High Yield Orthopaedic Notes
Definition
• Piriformis syndrome is a neuromuscular condition caused by irritation or compression of the sciatic nerve by the piriformis muscle.
• It produces buttock pain and sciatic-type symptoms without primary lumbar spine pathology.
• Often mimics lumbar disc herniation and radiculopathy.
Anatomy
Piriformis Muscle
Origin:
• Anterior surface of the sacrum
Insertion:
• Superior border of the greater trochanter
Action:
• External rotation of the hip in extension
• Abduction of the hip in flexion
Relationship to Sciatic Nerve
• Sciatic nerve usually passes beneath the piriformis muscle.
• Compression or irritation of the nerve can produce sciatica-like symptoms.
Pathophysiology
Causes include:
• Muscle spasm
• Hypertrophy of piriformis
• Inflammation
• Trauma to the buttock
• Repetitive overuse
• Anatomical variations of the sciatic nerve
Result:
• Compression of the sciatic nerve
• Buttock pain
• Referred pain down the lower limb
Clinical Features
Symptoms
• Deep buttock pain
• Pain radiating to the posterior thigh
• Occasionally pain extending below the knee
• Tingling or numbness in the leg
• Pain aggravated by:
• Sitting
• Climbing stairs
• Running
• Squatting
Clinical Clues
• Buttock pain predominates
• Symptoms often worsen with prolonged sitting
• Lumbar spine examination may be relatively normal
Differential Diagnosis
Lumbar Disc Herniation
Features favoring disc disease:
• Low back pain
• Positive straight leg raise
• Neurological deficit
• MRI evidence of disc prolapse
Other Conditions
• Lumbar spinal stenosis
• Sacroiliac joint dysfunction
• Hamstring syndrome
• Ischiofemoral impingement
• Hip pathology
Examination
Local Examination
• Tenderness over piriformis muscle in the buttock
• Reproduction of symptoms with stretching of the muscle
Special Tests
Straight Leg Raise Test
Purpose:
• Primarily evaluates lumbar disc herniation
Positive Test:
• Reproduction of radicular pain
Interpretation:
• Strongly suggests lumbar nerve root irritation
FAIR Test
(Flexion Adduction Internal Rotation Test)
Technique:
• Hip flexed
• Hip adducted
• Hip internally rotated
Positive Test:
• Reproduction of buttock pain or sciatic symptoms
Significance:
• Most commonly used test for piriformis syndrome
Lasegue-Type Maneuver
Technique:
• Hip flexion with knee extension
Positive Test:
• Reproduction of sciatic symptoms
Indicates:
• Sciatic nerve irritation
Important Distinction
FAIR Test
• Flexion
• Adduction
• Internal Rotation
Used for:
• Piriformis syndrome
FABER Test
• Flexion
• Abduction
• External Rotation
Used for:
• Sacroiliac joint pathology
• Hip pathology
Do not confuse the two tests.
Diagnostic Features Supporting Piriformis Syndrome
• Buttock tenderness
• Positive FAIR test
• Symptoms reproduced by stretching piriformis
• Absence of significant lumbar pathology
• Normal or non-diagnostic spinal imaging
Investigations
MRI Lumbar Spine
Purpose:
• Exclude disc herniation
• Exclude spinal causes of sciatica
MRI Pelvis
May demonstrate:
• Piriformis hypertrophy
• Muscle edema
• Anatomical variations
Electrophysiological Studies
Occasionally used to evaluate sciatic nerve involvement.
Treatment
Conservative Management
First-line treatment:
• Activity modification
• NSAIDs
• Physiotherapy
• Stretching exercises
• Core strengthening
• Hip abductor strengthening
Injection Therapy
Options:
• Local anesthetic injection
• Corticosteroid injection
• Ultrasound-guided piriformis injection
Purpose:
• Diagnostic
• Therapeutic
Surgical Treatment
Rarely required
Indications:
• Persistent symptoms
• Failure of prolonged conservative treatment
• Confirmed sciatic nerve compression
Procedure:
• Piriformis release
• Sciatic nerve decompression
Key Take Home Messages
• Piriformis syndrome is a cause of non-spinal sciatica.
• Buttock pain is the dominant symptom.
• FAIR test is the most useful clinical test.
• Always differentiate from lumbar disc herniation.
• Tenderness over the piriformis muscle supports the diagnosis.
• Most patients improve with conservative treatment.
Exam Pearls
• Piriformis originates from the anterior sacrum and inserts on the greater trochanter.
• Sciatic nerve compression by piriformis produces sciatica-like symptoms.
• FAIR test = Flexion + Adduction + Internal Rotation.
• FABER test evaluates hip and sacroiliac pathology, not piriformis syndrome.
• Positive straight leg raise is more suggestive of lumbar disc herniation.
• Piriformis syndrome remains a diagnosis of exclusion.
This format aligns well with your previous summaries on FABER test, Gaenslen test, straight leg raise test, and other orthopaedic examination maneuvers.





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