OrthopaedicPrinciples.com

Integrating Principles and Evidence

Integrating Principles and Evidence

-Oncology

Giant Cell Tumor

Epidemiology Giant cell tumors account for approximately five percent of all primary bone tumors. Most commonly affect patients between twenty and forty years of age. There is a slight female predominance. Tumors usually present as solitary lesions. Multicentric giant cell tumors are rare, occurring in one to two percent of cases, and may be synchronous […]

Osteosarcoma

  Definition Osteosarcoma is a malignant primary bone tumor defined by the production of osteoid by malignant cells. It is the most common non-hematologic primary malignancy of bone. Incidence Annual incidence is approximately one to three cases per million population. Occurs worldwide with no significant racial predilection. Age Distribution Osteosarcoma can occur at any age. […]

Chondrosarcoma

  Definition Chondrosarcoma is a malignant primary bone tumor characterized by the production of a cartilaginous matrix by malignant cells. It is the second most common non-hematologic primary malignancy of bone, after osteosarcoma. Incidence Overall incidence is approximately half that of osteosarcoma. Occurs worldwide with no significant racial predilection. Age Distribution Primary chondrosarcoma: Peak incidence […]