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Integrating Principles and Evidence

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-Basic Sciences

Antalgic Gait

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA Definition Antalgic gait is a painful gait pattern. The patient avoids spending time on the affected leg due to pain. The goal is to reduce weight-bearing on the painful extremity. Normal Gait Cycle Stance phase: 60% of the gait cycle Swing phase: 40% of the gait […]

Biomechanics of Hand and Wrist

Courtesy: Rishi Dhir, FRCS Orth, Harlow, UK Overview Understanding normal biomechanics is essential before analyzing pathology of the hand and wrist. For conceptual learning, biomechanics can be divided into two major components: finger biomechanics and wrist and carpal biomechanics. Finger movement involves coordinated interaction between joints and muscular mechanisms. Joints of the Fingers Three major […]

Vitamin D Deficiency and its Implications

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA VITAMIN D DEFICIENCY Vitamin D is important for the proper maturation and development of bone and it also boosts our immunity. We use the term “deficiency” if the vitamin D level is below 20 ng/ ml. We use the term “insufficiency” if the vitamin D level […]

Trabecular Pattern of the Proximal Femur

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA   TRABECULAR PATTERN OF THE PROXIMAL FEMUR There are important trabecular patterns in the proximal femur. It occurs according to Wolff’s Law in response of the bone to stress. There is a primary tensile trabeculae and a primary compression trabeculae. There also are secondary tensile and […]

All about Osteocytes

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA Overview of Osteocytes Osteocytes are the most abundant cells in bone tissue. They represent approximately 90 percent of all bone cells. Osteocytes originate from mesenchymal stem cells through osteoblast differentiation. Some osteoblasts become embedded in mineralized bone matrix and transform into osteocytes. Structure of Osteocytes Osteocytes […]

Osteoblast, Osteocytes and Osteoclast

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA Overview of Bone Remodeling Bone remodeling is a continuous physiological process that maintains skeletal integrity. It involves a balance between bone formation and bone resorption. Osteoblasts are responsible for bone formation. Osteoclasts are responsible for bone resorption. Both cell types work in a coordinated manner to […]

Genetics in Orthopaedics

Courtesy: Amr Abdelgawad, Maimonaiedes Medical Centre, New York, USA Overview Genetic abnormalities frequently affect the musculoskeletal system. Many skeletal dysplasias, connective tissue disorders, and neuromuscular diseases have identifiable gene mutations. Understanding these genes helps explain clinical features and inheritance patterns. Genetic Disorders with Musculoskeletal Manifestations Osteogenesis imperfecta – mutation in COL1A1 gene affecting type I […]

Basic science for Orthopaedic Boards

Courtesy: Amr Abdelgawad, Maimonaides Medical Centre, Brooklyn, NYC, USA

Bone and Cartilage Histology, Collagen

Courtesy: Amr Abdelgawad, Maimonaides Medical Centre, NY, USA Types of Bone Histology   Organized Bone (Lamellar Bone)   Cortical Bone – Forms the cortex of long bones. – Located in the shaft of bones such as the femur and tibia. – Dense with low porosity. – Lower surface area for the same bone volume. – […]

The Clotting cascade and Anti-thrombotic Medications

Courtesy: Amr Abdelgawad, Maimonaides Medical centre, NY, USA Overview – Blood clot formation and prevention are critical concepts in orthopedic surgery. – Surgical procedures, prolonged immobilization, and trauma increase the risk of deep vein thrombosis and pulmonary embolism. – Understanding the coagulation cascade, diagnostic features of pulmonary embolism, and mechanisms of antithrombotic medications is essential […]

Biomechanics of the Hip Joint

Courtesy: Prof Lalit Maini, MAMC, NewDelhi

Basic Principles of Fracture Healing

Courtesy: Dr Samir Qureshi, The Young Orthopod Channel FRACTURE HEALING Fracture Healing is a specialised type of wound healing consisting of a sequence of inflammation, repair and remodelling that helps to restore an injured bone. The way a fracture heals depend on the amount of movement occurring between the fracture fragments. When some amount of […]

Osseous tissue Cell anatomy and Matrix physiology

Courtesy: Prof Knoppy Bone has Cellular and Noncellular composition Four types of cells are found in bones: Osteoprogenitor cells, Osteoblasts, Osteocytes and Osteoclasts Osteoblasts are involved in bone deposition The Osteoclasts are large multinucleate Giant cells with a ruffled border, and are involved in bone absorption. Bone has orgnanic and inorganic component. Organic component consists […]

Physeal Zones and Abnormalities

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA This video describes the different physeal zones & their abnormalities. Growth plate has 3 zones- Reserve zone, proliferative zone & hypertrophic zone. Hypertrophic zone is again divided into zone of maturation , zone of degeneration & zone of provisional calcification. Reserve zone is the area where […]

Types of Collagen and its implications

Courtesy: Prof Nabil Ebraheim, University of Toledo, Ohio, USA This video describes about various types of collagen. Collagen is made by fibroblasts & there are about 20 types of collagen which constitutes 20% of our body proteins Type 1 collagen accounts for 90% of our body collagen & is associated with primary bone healing. It […]

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